Self-healing and flame retardant waterborne polyurethanes (WPU) consisting of isophorone diisocyanate (IPDI) and polypropylene glycol (PPG), 2-Hydroxyethyl disulfide (HEDS) and OP550 were prepared. The effect of OP550 on self-healing ability of waterborne polyurethanes was studied. And the result showed that when the OP550 content is up to 20%, the limiting oxygen index reached 29.0% which is increased by 7.4% in comparison to HWPU; the healed tensile strength is 4.71 MPa and self-healing efficiency is 107.9% for 3 h at 80 ℃.