The preparation of conventional bisphenol A-based epoxy resins is highly dependent on fossil energy, and in order to avoid overdependence on petrochemical resources, the development of renewable bio-based resins to replace conventional petroleum-based epoxy resins has received widespread attention. However, bio-based epoxy resins usually have low mechanical properties and poor degradation properties due to the highly permanent cross-linking network of conventional epoxy resins. In this study, an epoxy resin was prepared from camphoric acid, which was cured with polyether amine D230 to prepare a high mechanical property and degradable crosslinked network of camphoric acid-based epoxy resin. It was shown that the camphoric acid-based epoxy resin exhibited excellent mechanical properties due to the introduction of a rigid five-membered ring skeleton structure of camphoric acid, with a tensile strength of up to 75 MPa. In addition, due to the introduction of an ester group into the camphoric acid-based epoxy resin network, the material exhibited excellent degradation properties. The resin can be rapidly degraded in 100 ℃ in ethanolamine within 250 min by the amidation reaction between the ester group and the amino group.